MyBioSource.com's MOUSE ANTI HUMAN GRANZYME A is a Mouse monoclonal antibody. The MOUSE ANTI HUMAN GRANZYME A Antibody was generated using CTLA3, Granzyme A, Gzma, HFSP, and SE1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
MBS212504 recognises Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection